Top 22 late night restaurants in South Loop

When the clock strikes midnight, finding a place to grab a bite in South Loop can be a challenge. However, there are a few hidden gems that cater to those night owls seeking a late-night repast. From cozy diners to upscale eateries, these late night restaurants in South Loop offer delicious menus and welcoming atmospheres, perfect for satisfying your after-hours cravings. Let's explore some popular options!

1. Flo & Santos in South Loop

Open until 3 AM on weekends, live music on select nights, authentic Italian cuisine

TOPICS

  • Social Gatherings
  • American Cuisine
  • Italian Cuisine
  • Mexican Cuisine

2. Half Sour

Open until 3AM on weekends, retro decor, and Jewish deli classics

TOPICS

  • Social Gatherings
  • American Cuisine
  • Happy Hours
  • Downtown Spots

3. Cafe Bionda

Serves organic and locally sourced ingredients, vegetarian and vegan friendly

TOPICS

  • Personal Celebrations
  • Italian Cuisine
  • Mid-Range

4. First Draft in South Loop

Vintage diner atmosphere, 24/7 operating hours, famous celebrity hangout

TOPICS

  • Social Gatherings
  • American Cuisine
  • Affordable Nightlife
  • Downtown Spots

5. Weather Mark Tavern

Historic building with a cozy and welcoming atmosphere

TOPICS

  • American Cuisine
  • Cheap Eats
  • Downtown Spots

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6. Lou Malnati's Pizzeria in South Loop

Family-owned pizzeria since 1971, uses aged Wisconsin mozzarella

TOPICS

  • Italian Cuisine
  • Mid-Range
  • Downtown Spots

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7. Fatpour Tap Works - McCormick in South Loop

Featuring an impressive beer list and a laid-back atmosphere

TOPICS

  • American Cuisine
  • Vegetarian Options
  • Mid-Range
  • Downtown Spots

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8. Bar Louie - Printers Row

Located in Printers Row, downtown Chicago with a lively atmosphere

TOPICS

  • American Cuisine
  • Mid-Range

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9. Taco Maya

Offers a salsa bar and caters to vegetarian and gluten-free diets

TOPICS

  • Mexican Cuisine
  • Cheap Eats
  • Downtown Spots
  • Dinner

10. TAK Korean Bistro & Karaoke

Spacious karaoke rooms for private events, friendly service

TOPICS

  • Asian Cuisine
  • Social Gatherings
  • Downtown Spots

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11. Pizano's Pizza & Pasta

Family owned and operated since 1950, using original recipes and fresh ingredients.

TOPICS

  • Italian Cuisine
  • Budget-Friendly Eats
  • Hidden Gems

12. White Palace Grill

A staple in the Chicago nightlife scene since 1933, cash-only policy adds to the vintage charm

TOPICS

  • American Cuisine
  • Budget-Friendly Eats
  • Downtown Spots

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13. Mercat a la Planxa

Features a lively atmosphere with live flamenco dancing on weekends

TOPICS

  • Mediterranean Cuisine
  • Downtown Spots
  • Dinner
  • Corporate Events

14. Kitty O'Sheas

Live Irish music and sports on large screen TVs

TOPICS

  • Asian Cuisine
  • Happy Hours
  • Downtown Spots

15. Art of Pizza on State Street

Open until 1am on weekdays and 2am on weekends

TOPICS

  • Italian Cuisine
  • Downtown Spots
  • Mid-Range
  • Vegetarian Options

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16. Harold’s Chicken #88 Meets Beer

Family-owned business since 1950, known for their secret chicken recipe.

TOPICS

  • Downtown Spots
  • Dinner
  • Late Night

17. Woven + Bound Restaurant

Unique book-themed ambiance with wall-to-wall bookshelves

TOPICS

  • Mexican Cuisine
  • Vegetarian Options
  • Affordable Nightlife

18. Subway

Open till late, central location, offers catering services

TOPICS

  • American Cuisine
  • Budget-Friendly Eats

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19. Third Star

Live music on weekends, nostalgic atmosphere, famous celebrity spot

TOPICS

  • American Cuisine
  • Downtown Spots
  • Dinner

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20. All Star Seafood and Sports

Spacious seating, numerous TVs, extensive drink menu

TOPICS

  • Mexican Cuisine
  • Budget-Friendly Eats
  • Downtown Spots
  • Dinner

21. 720 South Bar & Grill

Open until 2am on Fridays and Saturdays

TOPICS

  • American Cuisine
  • Gluten-Free
  • Mid-Range
  • Downtown Spots

22. Bureau Bar and Restaurant

Housed in a historic building with a speakeasy vibe

TOPICS

  • American Cuisine
  • Vegan Options
  • Mid-Range
  • Downtown Spots