Top 22 late night restaurants in South Loop
When the clock strikes midnight, finding a place to grab a bite in South Loop can be a challenge. However, there are a few hidden gems that cater to those night owls seeking a late-night repast. From cozy diners to upscale eateries, these late night restaurants in South Loop offer delicious menus and welcoming atmospheres, perfect for satisfying your after-hours cravings. Let's explore some popular options!
- 1. Flo & Santos in South Loop
- 2. Half Sour
- 3. Cafe Bionda
- 4. First Draft in South Loop
- 5. Weather Mark Tavern
- 6. Lou Malnati's Pizzeria in South Loop
- 7. Fatpour Tap Works - McCormick in South Loop
- 8. Bar Louie - Printers Row
- 9. Taco Maya
- 10. TAK Korean Bistro & Karaoke
- 11. Pizano's Pizza & Pasta
- 12. White Palace Grill
- 13. Mercat a la Planxa
- 14. Kitty O'Sheas
- 15. Art of Pizza on State Street
- 16. Harold’s Chicken #88 Meets Beer
- 17. Woven + Bound Restaurant
- 18. Subway
- 19. Third Star
- 20. All Star Seafood and Sports
- 21. 720 South Bar & Grill
- 22. Bureau Bar and Restaurant
1. Flo & Santos in South Loop
Open until 3 AM on weekends, live music on select nights, authentic Italian cuisine

Flo & Santos, a popular restaurant, offers a variety of meal options including Lunch, Dinner, Late Night, and Drinks. The food standouts are their specialty pizzas, specifically the Buffalo Chicken and Sausage with Sauerkraut options. These pizzas are delicious and highly recommended.
In addition to their food, Flo & Santos has a good selection of beers and offers occasional beer specials. However, the music can sometimes be too loud, which may make it difficult to have a comfortable conversation. Despite this, the restaurant's food is definitely worth a visit.
TOPICS
- Social Gatherings
- American Cuisine
- Italian Cuisine
- Mexican Cuisine
2. Half Sour
Open until 3AM on weekends, retro decor, and Jewish deli classics

Half Sour is a great option for those looking for a late-night dining spot in the South Loop. The atmosphere is lively and energetic, making it a perfect place to hang out with friends or grab a bite to eat after a night out. The menu offers a variety of options, ensuring there is something for everyone.
What sets Half Sour apart is its commitment to staying open until 2 AM on weekends. This extended kitchen hours means that hungry patrons can still enjoy a delicious meal even in the late-night hours. Whether you're looking for a quick snack or a full meal, Half Sour has got you covered. The food is consistently delicious, with a focus on quality ingredients and creative flavor combinations. Overall, Half Sour is a solid choice for anyone in search of a great spot for late-night dining.
TOPICS
- Social Gatherings
- American Cuisine
- Happy Hours
- Downtown Spots
3. Cafe Bionda
Serves organic and locally sourced ingredients, vegetarian and vegan friendly

Cafe Bionda is an excellent choice for those looking for a late-night dining experience. Its cozy atmosphere and consistently delicious food make it a great spot for gathering with friends. The service at Cafe Bionda is friendly, adding to the overall positive experience.
The Limoncello Martini is a standout drink on the menu. Visitors to Cafe Bionda should not miss the opportunity to try this delightful cocktail. Whether enjoying a meal or just having a drink, Cafe Bionda is a wonderful place to spend a late night.
TOPICS
- Personal Celebrations
- Italian Cuisine
- Mid-Range
4. First Draft in South Loop
Vintage diner atmosphere, 24/7 operating hours, famous celebrity hangout

This place has a great late-night vibe, perfect for those looking for a place to eat after most restaurants have closed. The burgers and wings are standouts on the menu, and the service is impressive even when it's late at night.
If you're a night owl, this is the ideal spot for you. The kitchen remains open until 2 AM, so you can satisfy your hunger even in the wee hours of the morning. The delicious burgers and wings make it worthwhile to stay up late for a tasty meal.
TOPICS
- Social Gatherings
- American Cuisine
- Affordable Nightlife
- Downtown Spots
5. Weather Mark Tavern
Historic building with a cozy and welcoming atmosphere

Weather Mark Tavern is a popular choice for those seeking late night dining options. The menu at this establishment offers a wide variety of dishes, ensuring that there is something for everyone. Apart from the extensive food selection, Weather Mark Tavern is also known for its exceptional service. The staff is attentive and friendly, making guests feel welcome and well taken care of.
If you're looking for a place to satisfy your late night cravings, Weather Mark Tavern is an excellent choice. The kitchen remains open late into the night, allowing patrons to enjoy a hot and delicious meal even at odd hours. The food served is always fresh and flavorful, guaranteeing a satisfying dining experience. Whether you're in the mood for a hearty meal or a light snack, Weather Mark Tavern has got you covered.
TOPICS
- American Cuisine
- Cheap Eats
- Downtown Spots
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6. Lou Malnati's Pizzeria in South Loop
Family-owned pizzeria since 1971, uses aged Wisconsin mozzarella

Lou Malnati's is a great place to satisfy your late-night pizza cravings. The deep dish pizza is a must-try, even if you drop in late. The restaurant maintains a high standard of food quality and ambiance, making it an excellent choice for a late-night meal.
During our visit, we found Lou Malnati's to be welcoming and serving delicious food despite the late hour. The deep dish pizza was particularly noteworthy and lived up to its reputation. Regardless of the time of your visit, Lou Malnati's is committed to providing a top-notch dining experience.
TOPICS
- Italian Cuisine
- Mid-Range
- Downtown Spots
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7. Fatpour Tap Works - McCormick in South Loop
Featuring an impressive beer list and a laid-back atmosphere

After attending a late event at McCormick Place, a visit was made to Fatpour Tap Works. The restaurant offered a varied late-night menu with numerous options to choose from. The service provided was commendable, making the dining experience enjoyable.
Fatpour Tap Works ranks high among late-night restaurants in the area, with a reputation for serving fresh food in a lively atmosphere. Its lively ambiance complements the delectable menu, making it an ideal destination for post-event dining.
TOPICS
- American Cuisine
- Vegetarian Options
- Mid-Range
- Downtown Spots
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8. Bar Louie - Printers Row
Located in Printers Row, downtown Chicago with a lively atmosphere

The ambiance at this location is pleasant, and the service has been consistently good during my visits. One of the reasons I keep coming back is that it's one of the few places open late in the South Loop. However, the food served here is somewhat disappointing. Despite the average prices, the dishes do not stand out in terms of flavor or originality.
I have dined here multiple times, mostly for dinner, due to its late-night availability. The food quality is mediocre, yet the prices match what you would expect for this type of establishment. It would be nice to see some improvement in the food department, as it seems to be the only drawback in an otherwise decent dining experience.
TOPICS
- American Cuisine
- Mid-Range
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9. Taco Maya
Offers a salsa bar and caters to vegetarian and gluten-free diets

Taco Maya is a great spot to satisfy late-night taco cravings, as it stays open until 1 AM on weekends. After a night out, we decided to give it a try, and we were not disappointed. The late-night menu offerings were plentiful and delicious.
Our taste tests confirmed that everything we tried from Taco Maya was excellent. Whether you're looking for a quick and tasty snack or a full meal after a long night, Taco Maya's late-night menu is sure to deliver. With its late operating hours, it's an excellent option for those looking for a satisfying meal at an unusual hour.
TOPICS
- Mexican Cuisine
- Cheap Eats
- Downtown Spots
- Dinner
10. TAK Korean Bistro & Karaoke
Spacious karaoke rooms for private events, friendly service

Tak Korean Bistro & Karaoke is a fantastic place to have a good time with friends, particularly for karaoke. Although I didn't sample the food on this occasion, I am eager to do so on my next visit. The atmosphere at Tak is delightful and welcoming, making it an ideal spot for a memorable evening.
Tak Korean Bistro & Karaoke is a highly recommended destination in Chicago for food lovers and karaoke enthusiasts. Upon arrival, the establishment's inviting ambiance creates a positive and enjoyable mood. It promises to be an unforgettable experience, whether you choose to indulge in their culinary offerings or belt out your favorite tunes in their karaoke rooms.
TOPICS
- Asian Cuisine
- Social Gatherings
- Downtown Spots
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11. Pizano's Pizza & Pasta
Family owned and operated since 1950, using original recipes and fresh ingredients.

Pizano's Pizza is a popular choice for late night eats, known for its delicious pizza and friendly service. Located near McCormick Place, it's a convenient and welcoming spot for visitors and locals alike.
The pizza at Pizano's is a highlight, with both thin crust and deep dish options that are sure to satisfy. Even late at night, the service remains excellent, with staff who are committed to providing a great dining experience for their customers.
TOPICS
- Italian Cuisine
- Budget-Friendly Eats
- Hidden Gems
12. White Palace Grill
A staple in the Chicago nightlife scene since 1933, cash-only policy adds to the vintage charm

The White Palace Grill is a diner that serves eggs in a variety of ways, around the clock. The establishment attracts a diverse clientele including city workers, policemen, firemen, business people, college students, politicians, and even the afterhours club crowd. Despite the constant crowd, the food and service are highly regarded.
One popular menu item is the Pancho Villa omelette, which is known for its great flavors. The diner is a popular destination for many different types of people, and its doors are open 24 hours a day. Whether you're looking for a quick breakfast before work or a late-night snack, the White Palace Grill has something for everyone.
TOPICS
- American Cuisine
- Budget-Friendly Eats
- Downtown Spots
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13. Mercat a la Planxa
Features a lively atmosphere with live flamenco dancing on weekends

Mercat a la Planxa is a highly recommended restaurant for late-night dining, known for its exceptional service and excellent food. The tapas offered are delicious and perfect for sharing.
The ambiance at Mercat a la Planxa is ideal for a night out, with a lively atmosphere that makes it a great spot for socializing. The food is top-notch, made from high-quality ingredients and presented in an appealing manner. Whether you're looking for a quick bite or a full meal, this restaurant is sure to deliver.
TOPICS
- Mediterranean Cuisine
- Downtown Spots
- Dinner
- Corporate Events
14. Kitty O'Sheas
Live Irish music and sports on large screen TVs

Kitty O'Sheas is a wonderful choice for a late-night visit, offering friendly service and delicious food. The atmosphere is comfortable, making it an ideal location to relax after a long day. The food served is of good quality, adding to the overall positive experience of the restaurant.
Late-night dining at Kitty O'Sheas is a great option, especially after attending a concert or event. The cozy ambiance of the restaurant provides a welcoming environment for patrons looking for a late-night bite. Whether it's for unwinding after a long day or looking for a place to eat after a night out, Kitty O'Sheas is a perfect choice.
TOPICS
- Asian Cuisine
- Happy Hours
- Downtown Spots
15. Art of Pizza on State Street
Open until 1am on weekdays and 2am on weekends

As a no-frills pizza place, this establishment offers both eat-in and take-out options, although seating is limited and bathrooms are not available. The menu includes pizza by the slice and footlong sandwiches, with quick and friendly service. The pizza was enjoyed more than that of a popular tourist chain and is offered at a more affordable price. A variety of pizza slices are ready to be served, allowing for minimal wait times.
During lunchtime, this pizza place is a popular destination with a constant flow of customers. Patrons have the choice of thin, pan, or stuffed crust pizzas with a wide variety of toppings. Each individual was able to order the exact slice they wanted without any waiting, and luckily, a table was available for seating. The pizza is served in big slices at decent prices, providing a true taste of Chicago.
TOPICS
- Italian Cuisine
- Downtown Spots
- Mid-Range
- Vegetarian Options
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16. Harold’s Chicken #88 Meets Beer
Family-owned business since 1950, known for their secret chicken recipe.

Harold's Chicken #88 is a restaurant that offers a casual and relaxed atmosphere, serving a menu of wings, waffles, and a variety of sauces. The cashier/bartender is knowledgeable and provides excellent recommendations, ensuring that customers can enjoy well-seasoned wings. The restaurant provides a space for adults to unwind, offering a staple food from their childhood along with adult beverages.
The service at Harold's Chicken #88 is quick and efficient, and the restaurant is neat and has a great atmosphere. The chicken is made fresh to order, and it tastes great while being surprisingly not greasy. Prices are reasonable, and the location has a well-stocked bar and a clean kitchen. This establishment has quickly become a new favorite Chicago chicken spot for many.
TOPICS
- Downtown Spots
- Dinner
- Late Night
17. Woven + Bound Restaurant
Unique book-themed ambiance with wall-to-wall bookshelves

The establishment was visited late at night and was still surprisingly busy. While the atmosphere was lively, the food was found to be overpriced considering the quality. However, the service received was commendable and efficient. It is uncertain if a return visit for a late-night meal would be made due to the overpriced food.
A stop was made at the establishment for a late-night snack. Unfortunately, the drinks were not prepared correctly, but the bartender was quick to acknowledge the mistake and attempted to rectify it. The place was notably busy, which suggests a popular spot even during late hours. Overall, despite the drink mishap, the attentive service left a positive impression.
TOPICS
- Mexican Cuisine
- Vegetarian Options
- Affordable Nightlife
18. Subway
Open till late, central location, offers catering services

My girlfriend and I stopped by a food establishment late at night to grab a sandwich. The service we received was excellent, and the cleanliness of the establishment was impressive. The staff was fully equipped, working together seamlessly, and there were no signs of pests.
The sandwich we ordered was decent, but it was the service and cleanliness that truly stood out. It was refreshing to see a place that took such pride in its late-night operations. Although the sandwich was not the highlight of our visit, the overall experience left a positive impression on us.
TOPICS
- American Cuisine
- Budget-Friendly Eats
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19. Third Star
Live music on weekends, nostalgic atmosphere, famous celebrity spot

Third Star is a popular destination for those seeking a late-night meal. The restaurant offers a diverse menu and excellent service, making it an ideal spot to relax and enjoy a meal after a long day. On a recent visit, we stopped by Third Star late at night after a conference. We were immediately impressed by the friendly and attentive staff, who made us feel welcome and well taken care of.
The menu at Third Star features a wide variety of options, ensuring that there is something for everyone. We opted for a few dishes to share, and each one was delicious and satisfying. From the flavorful appetizers to the hearty entrees, every dish was cooked to perfection and presented beautifully. Based on our experience, we would highly recommend Third Star for anyone looking for a great meal at any time of the day, but particularly for late-night eats.
TOPICS
- American Cuisine
- Downtown Spots
- Dinner
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20. All Star Seafood and Sports
Spacious seating, numerous TVs, extensive drink menu

This establishment is highly recommended for late night dining, where guests can enjoy a lively atmosphere and fresh seafood. After a late-night event, such as a game, the restaurant remains bustling with energy. One standout dish is the crab legs, which are a popular choice among diners.
The seafood selection is fresh and the restaurant's vibe is perfect for a late night out. Even when arriving late, the restaurant is still busy and lively. The crab legs, in particular, have been praised for their quality and taste. It's clear that the establishment prioritizes excellent service, as many guests have noted their positive experiences with the staff.
TOPICS
- Mexican Cuisine
- Budget-Friendly Eats
- Downtown Spots
- Dinner
21. 720 South Bar & Grill
Open until 2am on Fridays and Saturdays

The 720 Bar and Grill at the Hilton offers a highly satisfying lunch buffet, ideal for those attending conference events. The service is exceptional, with several staff members providing warm and attentive care to diners. Tables are spacious, allowing for comfortable dining and the review of conference materials.
During a recent visit, the service in 720 Bar and Grill was phenomenal. Managers, servers, bartenders, busboy, and the chef all engaged with diners. Drinks and food were delicious, and the atmosphere was outstanding. Prices were affordable, making it an excellent choice for both lunch and dinner.
TOPICS
- American Cuisine
- Gluten-Free
- Mid-Range
- Downtown Spots
22. Bureau Bar and Restaurant
Housed in a historic building with a speakeasy vibe

Bureau Bar and Restaurant is a lively spot with a vibrant atmosphere, often featuring DJ-hosted R&B nights. The menu offers a range of options, including salmon and tacos, although the flavor may vary between dishes. The staff is dedicated to providing excellent customer service, frequently going above and beyond to accommodate guests. However, prices can be steep, with some items seeming overpriced.
During a recent visit, the waitress was extremely friendly and the food was delicious with generous portions, all at a reasonable price. The ambiance was enhanced by nice music and a chill vibe. The drinks were also enjoyable, contributing to a great time had by the visitors. Overall, Bureau Bar and Restaurant is a nice place for a fun night out with friends, particularly due to the attentive staff and enjoyable atmosphere.
TOPICS
- American Cuisine
- Vegan Options
- Mid-Range
- Downtown Spots